Resting-proliferative transition in cultured mammalian cells.
Natl Cancer Inst Monogr, 1978/5;(48):81-5.
PMID: 219364
Abstract
Cell lines established in culture have been tested for their ability to enter a resting state upon serum step-down. The reentry of resting cells into a proliferative state has been studied. This transition between states of resting and of proliferation is considered a manifestation in cell cultures of physiologic growth regulatory mechanisms. The regulatory effects of hormones and hormone-like peptide growth factors on the resting-proliferative transition are analyzed.
MeSH terms
Adrenal Glands; Adrenocorticotropic Hormone; Animals; Cell Cycle; Cell Division; Cell Line; Culture Media; Cyclic AMP; DNA; Glucocorticoids; Interphase; Mice
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