An immunoperoxidase study on herpes simplex virus encephalitis.
J Neuropathol Exp Neurol, 1978/11-1978/12;37(6):790-5.
PMID: 216784
Impact factor: 3.148
Abstract
Using formalin-fixed, paraffin-embedded sections, indirect immunoperoxidase studies were performed on 3 autopsied and 1 biopsied cases of herpes simplex virus (HSV) encephalitis. Specific reaction was observed in all 4 cases. Distinct stain was observed both in neurons and in glial cells. Electron microscopic studies performed on the same material revealed HSV particles stained with electron-dense reaction products. The advantages and disadvantages of the use of formalin-fixed, paraffin-embedded material in immunoperoxidase studies of viral disease are discussed.
MeSH terms
Brain; Cell Nucleus; Cytoplasm; Encephalitis; Herpes Simplex; Humans; Immunoenzyme Techniques; Neuroglia; Neurons; Simplexvirus
More resources
EndNote: Download