Beta-oxidation in peroxisomes of brown adipose tissue.
Biochim Biophys Acta, 1978/12/22;531(3):353-6.
Kramar R, Hüttinger M, Gmeiner B, Goldenberg H
PMID: 216397
Abstract
Peroxisomes and mitochondria from brown adipose tissue of the rat were separated by differential pelleting and isopycnic gradient centrifugation. Both fractions oxidized palmitoyl-CoA with comparable specific activities. Unlike the mitochondrial beta-oxidation the peroxisomal activity was not influenced by carbon monoxide. Peroxisomal beta-oxidation together with carnitine acetyl-transferase, which is also located in peroxisomes, might be involved in chemical thermogenesis by delivering acetyl groups to the mitochondria.
MeSH terms
Adipose Tissue, Brown; Body Temperature Regulation; Catalase; Fatty Acid Desaturases; Microbodies; Mitochondria; NAD; Organoids; Oxidation-Reduction; Palmitoyl Coenzyme A
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