In vitro effect of transfer factor on the cyclic nucleotide level of human lymphocytes in chronic lymphocytic leukaemia and of mouse lymphocytes.
Acta Med Acad Sci Hung, 1978;35(1):43-6.
Kalmár L, Nékám K, Láng I, Kelemen G, Gergely P
PMID: 216215
Abstract
In the present study transfer factor (TF) failed to produce any change in the cAMP- and cGMP-levels of lymphocytes of patients with chronic lymphoid leukaemia (CLL). This is attributed to the malignant transformation of the lymphocytes or to a changed proportion of different lymphocyte populations in CLL. Human TF leaves the cyclic nucleotide levels of splenic lymphocytes of BALB/c mice unaffected.
MeSH terms
Animals; Cyclic AMP; Humans; Leukemia, Lymphoid; Lymphocytes; Mice; Mice, Inbred BALB C; Nucleotides, Cyclic; T-Lymphocytes; Transfer Factor
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