[Enzymatic and morphologic studies on long-term perfused dog kidneys].
Z Exp Chir, 1978;11(5):353-60.
Templin R, Putzke H, Nagel HR, Seemann B, Seiter H, Pietruschka U, Erdmann T, Schill H
PMID: 216173
Abstract
21 canine and 12 human kidneys were submitted to long-term perfusion for 24 hours. During that time LDH-activity, histologic, enzyme-histochemic, and ultrastructural examinations were carried out. The findings proved that kidneys with lesser damage from ischemia showed lower activities during the first 4 to 6 hours than kidneys which were more injured before. The latter showed the same ultrastructural alterations as kidneys after perfusion for 24 hours, which suggests an irreversible partial damage of the organ.
MeSH terms
Albumins; Animals; Dogs; Electron Transport Complex IV; Humans; Kidney; Mitochondrial Swelling; Perfusion; Time Factors; Tissue Preservation
More resources
EndNote: Download