Thymidine kinase from herpes simplex virus phosphorylates the new antiviral compound, 9-(2-hydroxyethoxymethyl)guanine.
J Biol Chem, 1978/12/25;253(24):8721-7.
Fyfe JA, Keller PM, Furman PA, Miller RL, Elion GB
PMID: 214430
MeSH terms
Antiviral Agents; Guanine; Kinetics; Simplexvirus; Structure-Activity Relationship; Substrate Specificity; Thymidine Kinase
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