[Separation of catalytic and regulatory subunits of pigeon breast muscle protein kinase].

Biokhimiia, 1978/1;43(1):89-93.

Iusupova GI, Meshkova NP

PMID: 203342

Abstract
The separation of catalytic cAMP-independent and regulatory cAMP-binding subunits of pigeon breast muscle protein kinase was performed after the treatment of the holoenzyme by cAMP. The molecular weight of the homogeneous catalytic subunit is determined as 30,000. When catalytic and regulatory subunits were mixed, the decrease of phosphotransferase activity was observed.
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