[Test of an attenuated viral strain of TGE as a vaccine].
Vet Med Nauki, 1977;14(6):3-10.
Kristov S, Karadzhov I, Tatarov G, Ignatov G, Khristova V
PMID: 202064
Abstract
A live vaccine was produced using a local strain P of the virus of the transmissive gastroenteritis, arrenuated in cell cultures. The vaccinated pregnant sows had high-titer serum and colostrum virus-neutralizing antibodies. In the first days following farrowing there were in the colostrum ummunoglobulins of the Igg class that prevailed, however, IgA and IgM proved more effective in the virus-neutralizing test. Newborn pigs acquired passive immunity at about the 24th hour after the intake of colostrum. They withstood a challenge with a virulent virus.
MeSH terms
Animals; Antibodies, Viral; Colostrum; Coronaviridae; Drug Evaluation, Preclinical; Female; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Milk; Neutralization Tests; Pregnancy; Swine; Transmissible gastroenteritis virus; Vaccination; Vaccines, Attenuated; Viral Vaccines
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