Possible regulatory function of acetylcholine receptor in maintenance of retinotectal synapses.
Nature, 1977/9/15;269(5625):218-22.
PMID: 201850
Impact factor: 69.504
Abstract
alpha-Neurotoxins bind to cholinergic receptor, block transmission, and induce sprouting of retinal terminals in the toad tectum. New connections retain an orderliness that suggests a selective affinity between presynaptic terminals. The results suggest that postsynaptic cells exert a control, associated with receptors, on the growth of presynaptic terminals and on the maintenance of their synaptic connections.
MeSH terms
Acetylcholine; Animals; Bufo marinus; Bungarotoxins; Receptors, Cholinergic; Retina; Synapses; Synaptic Transmission; Tectum Mesencephali; Time Factors
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