[Effect of enteral administration of sodium ribonucleate on the synthesis of amino acyl t RNA in the liver and skeletal muscles of rabbits in experimental hypercorticism].
Probl Endokrinol (Mosk), 1977/5-1977/6;23(3):100-2.
Germaniuk IaL, Goĭdash MM, Khaliavko PM
PMID: 196279
Abstract
Daily, for 14 days, rabbits of one group were injected with corticotropin, i.e. ACTH-zinc-phosphate (10 units/kg), whereas rabbits of another group were given (in addition) sodium ribonucleate (40 mg/kg) through a tube into the stomach. Formation of lysyl-tRNA, leucyl-tRNA, and alanyl-tRNA in the liver and the skeletal muscles proved to be significantly greater in the animals which received ACTH together with sodium ribonucleate, as compared to that in the animals given the hormone alone. Hyperglycemia, hepatomegaly, and emaciation were less pronounced in the animals given both the preparations.
MeSH terms
Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Animals; Intestines; Liver; Muscles; RNA, Transfer; Rabbits; Sodium
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