[Inactivation of stem cells by allogenic lymphocytes: competition between T1- and T2-subpopulations].
Biull Eksp Biol Med, 1977/6;83(6):709-11.
Ignat'eva GA, Man'ko VM, Rudneva TB
PMID: 18238
Abstract
Transplantation of the bone marrow cells with allogeneic T-lymphocytes to the irradiated hosts was accompanied by inactivation of the stem elements of the graft. The lymph node cells of T-mice (those deprived of B cells) were more active than the spleen cells of these mice. The stem cells inactivation was weakly expressed or absent in case of a combined acti-n of T-cells from the lymph nodes and the spleen.
MeSH terms
Animals; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Hybridization, Genetic; Lymph Nodes; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Radiation Chimera; Spleen; T-Lymphocytes; Transplantation, Homologous
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