Translation in vitro of vesicular stomatitis virus mRNA lacking 5'-terminal 7-methylguanosine.
Nature, 1976/7/01;262(5563):32-7.
PMID: 180425
Impact factor: 69.504
Abstract
The 5'-terminus 7-methylguanosine of vesicular stomatitis virus mRNA is not essential for translation of the mRNA. The 7-methylguanosine seems to have a mediating rather than an obligatory role in ribosome binding by the mRNA and in mRNA translation.
MeSH terms
Cell-Free System; Guanine Nucleotides; Kinetics; Peptide Chain Initiation, Translational; Protein Biosynthesis; RNA, Messenger; RNA, Viral; Ribosomes; Structure-Activity Relationship; Vesicular stomatitis Indiana virus
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