The effect of nerve growth factor on cycle AMP levels in superior cerival ganglia of the rat.

Proc Natl Acad Sci U S A, 1975/12;72(12):4769-71.

Nikodijevic B, Nikodijevic O, Yu MY, Pollard H, Guroff G

PMID: 174074

Impact factor: 12.779

Abstract
Nerve growth factor (NGF) produces a several-fold increase in the cyclic AMP concentration in rat superior cervical ganglia in organ culture within 5 min. An increase can be seen with as little as 40 ng/ml of NGF. Oxidized NGF is without effect. The increase in the cAMP concentration produced by NGF is prevented by the addition of antiserum to NGF.
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