A comparison of the in vitro cytotoxicity of daunorubicin and liposomal daunorubicin in pediatric acute leukemia.
Haematologica, 2006/11;91(11):1573-4.
Goemans BF, Zwaan CM, Reinhardt D, Gibson BE, Hählen K, Kaspers GJ
PMID: 17043024
Impact factor: 11.047
Abstract
Anthracyclines are effective in the treatment of leukemia, but their use is limited because of cardiotoxicity. Liposomal daunorubicin (L-DNR) is potentially less cardiotoxic than daunorubicin (DNR). We compared in vitro cytotoxicity in pediatric acute leukemia samples and found no significant differences between cytotoxicity of DNR and L-DNR.
MeSH terms
Adolescent; Child; Child, Preschool; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Liposomes; Male
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