[Cytogenetic study of 30 couples having had several spontaneous abortions].
Sem Hop, 1975/1/26;51(5):299-302.
Broustet A, Serville F, Meynie M, Moulinier J, Moretti G
PMID: 169572
Abstract
In 30 couples consulting after two or more failed pregnancies, the authors detected two women with reciprocal translocation in the heterozygous condition: t (5 ; 6) (q 35 ; q 21) in one case. t (5 ; 10) (q 15 ; q 25) in the other case. In both cases, there was, later, birth of a normal boy of karyotype 46, XY. It thus appears obvious that the balanced structural changes which occur in the fertility of these couples, reduces the latter.
MeSH terms
Abortion, Habitual; Adult; Chromosome Aberrations; Chromosomes, Human, 4-5; Chromosomes, Human, 6-12 and X; Female; Heterozygote; Humans; Male; Pregnancy; Translocation, Genetic
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