Light and electron microscopic study of dysplastic rosette-like structures occurring in the disorganized mature retina.
Albrecht Von Graefes Arch Klin Exp Ophthalmol, 1975;195(1):57-68.
PMID: 167600
Abstract
Histopathologic examination of six, adult human eyes revealed "rosette-like" structures in the retina which appear to have developed after maturation of the retina. These structures resemble dysplastic rosettes which are generally interpreted as a sign of maldevelopment of the retina (retinal dysplasia). The underlying lesions in the eyes of these patients were ocular ischemia, sickle-cell retinopathy, diabetic retinopathy, central retinal vein occlusion, and trauma. It is suggested that a distinction should be made between these degenerative-regressive changes and dysplastic rosettes which represent an abortive attempt of regeneration by germinal cells.
MeSH terms
Adult; Aged; Cell Nucleus; Child, Preschool; Congenital Abnormalities; Female; Humans; Inclusion Bodies; Male; Middle Aged; Neuroglia; Neurons; Photoreceptor Cells; Regeneration; Retina; Retinal Degeneration; Retinal Detachment
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