Cloning and characterization of the homologous genes of firefly luciferase in the mealworm beetle, Tenebrio molitor.
Insect Mol Biol, 2006/6;15(3):293-9.
Affiliations
PMID: 16756548
Impact factor: 3.424
Abstract
Three homologous genes of firefly luciferase were cloned from the non-luminous beetle Tenebrio molitor. Three gene products for homologues, TmLL-1, TmLL-2 and TmLL-3, showed fatty acyl-coenzyme A (acyl-CoA) synthetic activity, but not luciferase activity with firefly luciferin. The transcripts were detected through the developmental stages in T. molitor. These results suggested that firefly luciferase was evolved from a fatty acyl-coenzyme A synthetase by gene duplications in the insect.
MeSH terms
Amino Acid Sequence; Animals; Biological Evolution; Coenzyme A Ligases; Gene Expression Regulation, Developmental; Genes, Insect; Larva; Luciferases, Firefly; Luminescence; Molecular Sequence Data; Sequence Analysis, DNA; Sequence Homology; Tenebrio
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