Antibody response of genetically susceptible and resistant chickens to cell-free and attenuated JM-V leukosis strain and its influence on early type II (Marek's) leukosis infection.
Poult Sci, 1975/1;54(1):69-77.
PMID: 166367
Impact factor: 4.014
Abstract
Experiments were carried out to: 1) determine the antibody response of chickens to cell-free and attenuated preparations of JMV leukosis strain, 2) determine the differences in antibody response to these antigens between susceptible (P-line) and resistant (N-line) chickens by means of serum neutralization and indirect fluorescent antibody tests, 3) investigate the influence of maternal (passive) antibody on early (day-old) JMV vaccination and 4) investigate the influence of maternal antibody in chicks naturally exposed continuously to JM virus from day-old to 8 weeks of age on the pathogenesis of Type II leudosis (Marek's) infections and oncogenesis.
MeSH terms
Animals; Antibody Formation; Cell-Free System; Chickens; Cytopathogenic Effect, Viral; Fluorescent Antibody Technique; Herpesviridae; Herpesvirus 2, Gallid; Immunity, Maternally-Acquired; Injections, Intraperitoneal; Marek Disease; Neutralization Tests; Turkeys; Viral Vaccines; Virulence
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