Quantitative determination of urinary trichloroacetic acid as an index of trichloroethylene exposure by high performance liquid chromatography.
Acta Med Okayama, 1979/12;33(6):479-81.
PMID: 161473
Impact factor: 0.744
Abstract
A high performance lipuid chromatographic method for the determination of urinary trichloroacetic acid, a metabolite of trichloroethylene, is described. A stainless steel column packed with Hitachi gel 2618 (H form) was used and the mobile phase was one per cent aqueous phosphoric acid. Urine can be analyzed directly without any solvent extraction or pretreatment. The minimal detection limit was 0.5 micrograms per analysis. The present method is simple and specific, and can be performed within 10 min.
MeSH terms
Chromatography, High Pressure Liquid; Environmental Exposure; Humans; Trichloroacetic Acid; Trichloroethylene
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