Preliminary evaluation of 15 chemotherapeutic agents applied topically in the treatment of mycosis fungoides.
Cancer Treat Rep, 1979/4;63(4):619-21.
Argyropoulos CL, Lamberg SI, Clendenning WE, Fischmann AB, Jegasothy B, Zackheim H, Peck GL
PMID: 156069
Abstract
This is an interim report of a double-blind multi-institutional study to examine the effect of chemotherapeutic agents applied topically to patients with mycosis fungoides. To date, 41 patch tests have been completed using 15 drugs. Five of the drugs produced some improvement, four were highly irritating, and six had no effect. This patch-testing study is a prelude to more extensive therapy trials.
MeSH terms
Administration, Topical; Antineoplastic Agents; Clinical Trials as Topic; Double-Blind Method; Drug Eruptions; Drug Evaluation; Humans; Mycosis Fungoides; Skin Neoplasms
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