Depolymerization of brain microtubules by skeletal muscle myosin.
J Biochem, 1979/3;85(3):691-8.
PMID: 155054
Impact factor: 3.241
Abstract
Brain microtubules are found to disperse rods of skeletal muscle myosin and become decorated with amorphous aggregates of myosin. Then microtubules are partially depolymerized by myosin. Myosin shows high Mg2+-GTPase activity which is not influenced by microtubules, and induces the partial depolymerization of microtubules by exhaustion of GTP in the solution. H-meromyosin depolymerizes microtubules like myosin does. H-meromyosin is, however, contaminated with a trace amount of trypsin, which irreversibly depolymerizes microtubules.
MeSH terms
Adenosine Triphosphatases; Alkaline Phosphatase; Animals; Brain; GTP Phosphohydrolases; Guanosine Triphosphate; Macromolecular Substances; Microtubules; Muscles; Myosin Subfragments; Myosins; Rabbits; Swine; Trypsin; Tubulin
More resources
EndNote: Download