[Immunocytological studies of C cells with anti-calcitonin or antisomatostatin immunoserums in rats treated with vitamin D, thyroxine or benzyl-thiouracil].
C R Seances Soc Biol Fil, 1978;172(4):691-6.
Bugnon C, Fellmann D, Blahser S, Maurat JP, Bloch B
PMID: 154950
Abstract
In rats treated with vitamin D3, thyroxin or BTU alone or with associations of vitamin D3 + BTU or vitamin D + thyroxin, immunocytochemical studies with an anti-human calcitonin serum show a stimulating effect of vitamin D and of thyroxin and an inhibiting effect of BTU on the C cells of the thyroïd. These results are in agreement with the existence of functional relations between follicular and C cells. A few calcitonin-containing cells are immunoreactive to an anti-somatostatin serum. All the C cells contain both calcitonin and somatostatin when they are grouped in a single big interfollicular cluster.
MeSH terms
Animals; Calcitonin; Fluorescent Antibody Technique; Immune Sera; Immunoenzyme Techniques; Male; Rats; Somatostatin; Thiouracil; Thyroid Gland; Thyroxine; Vitamin D
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