Reversion and interallelic complementation at four urease loci in Neurospora crassa.

Mol Gen Genet, 1978/10/24;165(3):277-82.

Benson EW, Howe HB Jr

PMID: 154055

Abstract
Analysis of heat stability of urease in extracts of 24 revertants, six for each of four ure loci, revealed that at least one revertant for each locus had a heat stability about one-third that of wild type. Similar results were obtained with urease formed by interallelic complementation at the ure-2 and ure-4 loci, but interallelic complementation at the ure-1 and ure-3 loci produced insufficient urease activity for analysis. The data are interpreted to suggest, as a tentative model, a structural function for each of the four ure loci.
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