Zinc sulfate in acne vulgaris.
Arch Dermatol, 1978/12;114(12):1776-8.
Weimar VM, Puhl SC, Smith WH, tenBroeke JE
PMID: 153730
Abstract
The effects of orally administered zinc sulfate in 52 patients with mild to moderate acne vulgaris were compared to those of a placebo capsule. The numbers of comedones, papules, pustules, infiltrates, and cysts were counted at each visit over a 12-week period. Forty patients completed the study. Zinc appeared to have a somewhat beneficial effect on pustules but not on comedones, papules, infiltrates, or cysts. Fourteen patients (50%) in the zinc group had side effects of nausea, vomiting, or diarrhea. Six patients (21%) in the zinc group could not tolerate the nausea and withdrew from the study.
MeSH terms
Acne Vulgaris; Administration, Oral; Adolescent; Adult; Clinical Trials as Topic; Diarrhea; Female; Humans; Male; Nausea; Placebos; Vomiting; Zinc
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