[Aggression toward groups of male and female OF1 mice by a male congenere and survival to acute hypoxia].
C R Seances Soc Biol Fil, 1978;172(3):432-6.
PMID: 153168
Abstract
In OF1 mice, a 107 day-old mouse, isolated since 51 days, acts as an "aggressor" when introduced into a group of 10 males or into a group of 10 females of the age of 51 days. This results in fights and flights in the males' group and in copulations in the females' group. In 31 experiments, each performed on a total of 40 males and 40 females, it was observed that an acute DL50 hypoxia (inhalation of nitrogen) provokes a mortality significantly (p less than 0.001) higher in the male "aggressors" (95.16%) than in the groups of 10 aggressed mice (mortality: 64.26% for the males' groups and 52.65% for the females groups). Besides, compared to control groups without male "aggressor", the introduction of the male congener significantly (p less than 0.001) increases the acute hypoxic mortality in the females' but not in the males' groups.
MeSH terms
Acute Disease; Aggression; Animals; Female; Humans; Hypoxia; Male; Mice; Mice, Inbred Strains; Sex Factors; Sexual Behavior, Animal
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