[The fertility of trisomy 21 sufferers. One case (author's transl)].
Nouv Presse Med, 1978/8/26-1978/9/26;7(28):2459-60.
Grall JY, Le Goux AM, Le Marec B, Picard F, Larget-Piet L, Dubois J
PMID: 151263
Abstract
A case of pregnancy in a patient with trisomy 21 with birth of a hypotrophic infant, with a normal caryotype but multiple malformations. This case illustrates the limitations on antenatal diagnosis by amniocentesis. Study of the literature confirms the unfavourable foetal prognosis as a result of the risk of transmission of the chromosomal abnormality and, secondly, the prevalence of incest.
MeSH terms
Abnormalities, Multiple; Adult; Amniocentesis; Down Syndrome; Female; Fertility; Humans; Infant, Newborn; Karyotyping; Male; Pregnancy; Pregnancy Complications
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