[Localization of a 5alpha-reductase activity in the nuclear membranes of the anterior hypophysis of normal and castrated adult male rats].
C R Seances Soc Biol Fil, 1977;171(3):639-43.
Ducouret B, Samperez S, Jouan P
PMID: 144004
Abstract
A 5alpha-reductase activity may be found in purified nuclei from anterior pituitary of intact or castrated male rats. When nuclear membranes are separated from nucleoplams this enzymic activity is recovered in nuclear membranes. Following 7 days of castration, the 5alpha-reductase activity in nuclear membranes is increased by 105 % with regard to the activity in nuclear membranes from intact animals.
MeSH terms
3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Animals; Castration; DNA Replication; Male; Nuclear Envelope; Oxidoreductases; Pituitary Gland, Anterior; Protein Biosynthesis; RNA; Rats
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