[Value of myocardial mass measurements in the hemodynamic and angiographic evaluation of aortic stenosis: 70 cases].
Arch Mal Coeur Vaiss, 1977/6;70(6):607-16.
Nitenberg A, Lecarpentier Y, Geschwind H
PMID: 142454
Abstract
The prognosis of aortic stenosis is often evaluated according to clinical criteria; but it is well known that the myocardial mass is one of the important determinants of prognosis. Starting from the fact that the ratio systolic work/myocardial mass (WS/VM) is a stable one in normal subjects (0.81 +/- 0.03), we were able to divide up the 70 patients with congenital and acquired aortic stenosis into three groups as follows:--Group I. WS/VM greater than 0.87; this group is called hyperfunctional, and characterised by an increase in WS, and a myocardial mass which is ostensibly normal.--Group II: 0.87 larger than or equal to WS/VM larger than or equal to 0.75; this isofunctional group is characterised by parallel increases in mass and systolic work.--Group III: WS/VM less than 0.75; this group is called hypofunctional, and is characterised by an increase in mass unrelated to an increase in work. A comparison of the sensitivity of other parameters with that of WS/VM gives rise to optimism that the precision of determination of the prognosis will increase, as will that of the choice of the time to operative, but only those patients in groups I and II can expect a return to normal function and ventricular mass.
MeSH terms
Adolescent; Adult; Aged; Angiocardiography; Aortic Valve Stenosis; Cardiomegaly; Child; Child, Preschool; Female; Heart Ventricles; Hemodynamics; Humans; Male; Middle Aged; Myocardial Contraction; Prognosis
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