Mucopolysaccharidosis in a cat.
J Am Vet Med Assoc, 1976/8/01;169(3):334-9.
Cowell KR, Jezyk PF, Haskins ME, Patterson DF
PMID: 134013
Impact factor: 1.836
Abstract
A young adult female Siamese cat born of a mother-son mating was referred because of dwarfism, facial abnormalities, severe skeletal deformities, multifocal neurologic deficits, and retinal atrophy. Cats of similar appearance had been observed in a previous litter of the same parents. Metachromatic inclusion bodies were demonstrated in circulating leukocytes. The urine contained a high concentration of mucopolysaccharide, as detected by the toluidine blue spot test. The uronic acid content of the cetylpyridinium chloride-precipitable mucopolysaccharide in the urine was 17 times greater than that in the urine from a control cat of the same age and breed.
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