Effects of phenobarbitone, cinnarizine, and zoxazolamine on the development of right ventricular hypertrophy and hypertensive pulmonary vascular disease in rats treated with monocrotaline.
Cardiovasc Res, 1976/3;10(2):200-5.
Kay JM, Smith P, Heath D, Will JA
PMID: 132989
Impact factor: 13.081
Abstract
The results of this experiment suggest that the addition of zoxazolamine to the diet may prolong the survival and reduce the incidence of right ventricular hypertrophy and hypertensive pulmonary vascular disease in male rats given a single subcutaneous injection of monocrotaline. Phenobarbitone and cinnarizine were ineffective.
MeSH terms
Animals; Cardiomegaly; Cinnarizine; Hypertension, Pulmonary; Male; Phenobarbital; Piperazines; Pyrrolizidine Alkaloids; Rats; Zoxazolamine
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