Effect of (+)-catechin on renal and intestinal transport.
Experientia, 1976/1/15;32(1):87-9.
PMID: 129336
Abstract
The ability of dog renal cortex slices to accumulate beta-methyl-glucoside or glycine is enhanced by the flavonoid (+)-catechin at a concentration of 3.5 mM. This stimulatory effect is apparently due to a decreased rate of efflux of either substrate. On the other hand, the uptake of p-amino-hippuric acid and N1-methyl-nicotinamide is inhibited by (+)-catechin. The drug at the same concentration is without action on amino-acid transport by guinea-pig intestine in vitro.
MeSH terms
Aminohippuric Acids; Animals; Benzopyrans; Catechin; Dogs; Glycine; Guinea Pigs; In Vitro Techniques; Intestine, Small; Kidney Cortex; Methylglucosides; Niacinamide; Phenylalanine
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