An unusual side effect on the skin under high dose D-penicillamin treatment.

Z Rheumatol, 1975/11-1975/12;34(11-12):413-7.

Cegla UH, Kroidl RF

PMID: 128936

Impact factor: 1.53

Abstract
An unusual side effect on the skin after one year's high dosage (3,0 g/die) of D-Penicillamin-treatment is reported. The skin showed double-pin-sized vesicles and laceration after minor injuries. After reduction of the dosage to 1,8 g/die and bathing the hands three times/day for 2 minutes in 1% Tannin solution the skin lesions and wounds healed eventually.
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