[Stimulation of peripheral guinea pig blood lymphocytes by autologous epidermal cells].
C R Seances Acad Sci D, 1979/11/26;289(14):1041-4.
PMID: 121259
Abstract
Using a strictly autologous (and not syngeneic) mixed culture system in the guinea-pig, it was shown that Mitomycin C treated ear epidermal cells (E) were capable of stimulating peripheral blood lymphocytes (L) from the same animal. The proliferative response of the lymphocytes as measured by 3H thymidine incorporation, is optimal on the 5th day of culture, and when the ratio of the concentrations of the two cell populations (L : E) is 1 : 1. The autoreactivity of the lymphocytes varies with the animal.
MeSH terms
Animals; DNA Replication; Guinea Pigs; Lymphocyte Activation; Lymphocytes; Male; Mitomycins; Skin; Skin Transplantation; Thymidine; Transplantation, Autologous
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