A species comparison of 2,4-dinitrotoluene metabolism in vitro.

Experientia, 1979/12/15;35(12):1625-7.

Short RD, Dacre JC, Lee CC

PMID: 118052

Abstract
Postmitochondrial supernatants prepared from livers of mice, rats, rabbits, dogs, and monkeys metabolized 2,4-dinitrotulene. The pattern of metabolites was characterized in both sexes of the species examined. In addition, the pattern of metabolites was altered by varying incubation conditions and pretreating male rats with phenobarbital or SKF 525-A.
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