Correlative studies of axonal spheroids and Lafora-like bodies in aged dogs.
Acta Neuropathol, 1979/10;48(1):77-81.
PMID: 116474
Impact factor: 15.887
Abstract
The gracile nucleus and conus medullaris, the sites of predilection for spheroids and Lafora-like bodies, were examined light and electron microscopically in 91 dogs ranging from 1 month to 19 years of age. The number of both structures showed a tendency to increase with age. Spheroids have already been found in younger dogs before the appearance of Lafora-like bodies. In the aged dog, intra-spheroidal Lafora-like bodies were occasionally observed. Correlative studies may yield clues on the pathogenesis of aging phenomena in the CNS.
MeSH terms
Aging; Animals; Brain; Cytoplasmic Granules; Dogs; Epilepsies, Myoclonic; Medulla Oblongata; Microscopy, Electron
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