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Polyadenylate-polyuridylate enhancement of 7,12-dimethylbenz-anthracene skin carcinogenesis.

Experientia, 1979/9/15;35(9):1232-3.

Stenbäck F, Curtis G, Ryan W

PMID: 114414

Abstract
Double-stranded polynucleotide polyadenylate-polyuridylate (Poly AU) enhanced skin tumor formation in Swiss mice by 75% when injected prior to a single application of 7,12-dimethylbenzanthracene (DMBA). When given after the carcinogen application Poly AU did not significantly enhance tumor formation.
MeSH terms
9,10-Dimethyl-1,2-benzanthracene; Animals; Mice; Neoplasms, Experimental; Poly A-U; Skin Neoplasms
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