Comparative in vitro activity of ABT-773, a novel antibacterial ketolide.
Antimicrob Agents Chemother, 2001/7;45(7):2163-8.
Nilius AM[1], Bui MH, Almer L, Hensey-Rudloff D, Beyer J, Ma Z, Or YS, Flamm RK
Affiliations
PMID: 11408246
Impact factor: 5.938
Abstract
The in vitro activities of ABT-773, erythromycin, clarithromycin, and azithromycin were compared. ABT-773 was the most active compound against macrolide-susceptible Streptococcus pneumoniae, Streptococcus pyogenes, Staphylococcus aureus, Staphylococcus epidermidis, Listeria monocytogenes, and Enterococcus spp. and multidrug-resistant Streptococcus pneumoniae. It also had good activity against gram-negative and atypical respiratory tract pathogens and Helicobacter pylori.
MeSH terms
Anti-Bacterial Agents; Azithromycin; Clarithromycin; Drug Resistance, Multiple; Enterococcus; Erythromycin; Helicobacter pylori; Humans; Ketolides; Microbial Sensitivity Tests; Staphylococcus; Streptococcus; Time Factors
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