Hypersomnia with periodic breathing (an acromegalic Pickwickian).
Otolaryngology, 1978/11-1978/12;86(6 Pt 1):ORL-897-903.
Romanczuk BJ, Potsic WP, Atkins JP Jr
PMID: 113749
Abstract
The syndromes of Pickwickian, Ondine's curse, and primary alveolar hypoventilation are respiratory disorders manifesting increased sleepiness and irregular respiratory rhythms. These disorders are currently grouped as hypersomnia with periodic breathing (HPB). Polygraphic techniques have lead to a reasonable hypothesis as to the pathophysiology of the multiple variants of HPB. Discernible causes of HPB have been attributed to both central and peripheral factors. Peripheral factors encompass those conditions relating to upper airway obstruction. An acromegalic person suffering the HPB syndrome secondary to laryngeal stenosis is described.
MeSH terms
Acromegaly; Adult; Airway Obstruction; Apnea; Disorders of Excessive Somnolence; Humans; Male; Obesity Hypoventilation Syndrome; Sleep Wake Disorders
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