Immunological properties of partially purified material with monocytosis-producing activity from Listeria monocytogenes.

Can J Microbiol, 1979/6;25(6):706-12.

Otokunefor TV, Shum DT, Galsworthy SB

PMID: 113069

Impact factor: 3.226

Abstract
A fraction rich in a monocytosis-producing activity (MPA) has been obtained by a two-stage chromatographic separation from a saline extract (SE) of Listeria monocytogenes. Like SE, the purified material elicits monocytosis and decreases the halftime of circulating monocytes. The purification of MPA eliminates the following found in SE: the in vitro mitogenic activity, the in vitro adjuvant activity, the immunosuppressive activity, and the granulocytosis-promoting and the lymphopenia-inducing activities.
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