Vasculature of the optic nerve in anencephaly.

Br J Ophthalmol, 1979/3;63(3):188-90.

Rootman J, Carvounis EP

PMID: 107961

Impact factor: 5.908

Abstract
The optic nerves and globes obtained from 6 anencephalics were studied histologically and compared to normal specimens obtained from 4 stillborn infants as well as 1 case of septo-optic dysplasia. Special emphasis was placed on examination of the optic nerve, and it was found that an average of 48 vessels per high-power field were seen posterior to the lamina cribrosa in anencephalics. In contrast, control globes had an average of 12 vessels per high-power field. This suggested that an increase in the vasculature of the hypoplastic optic nerve is a characteristic feature of anencephalics.
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