Study of plasma osmolarity during the treatment of diabetic ketoacidoses.
Med Interne, 1979/1-1979/3;17(1):67-77.
Ionescu-Tîrgovişte C, Bogathy I, Stamoran M, Mincu I
PMID: 107571
Abstract
Analysis of 610 cases of diabetic ketoacidosis, of which 210 severe cases, showed that before beginning the treatment 6.2% of the patients presented hypoosmolarity, 41.4% normoosmolarity (dysosmolarity) and 52.2% hyperosmolarity. In predominantly hypernatremic hyperosmolarity (5.9% of cases) the authors recommend weak alkaline hypotonic electrolytic solutions (222 mOsm/l). 5% glucose solution and insulin in small doses less than 5 U/h; in predominantly hyperglycemic hyperosmolarity, weak alkaline isotonic electrolytic solutions (309 mOsm/l) and insulin in medium doses (6--8 U/h); in exclusively hyperglycemic hyperosmolarity, hypertonic electrolytic solutions (395 mOsm/l) associated with sufficient insulin dosis (8--12 U/h).
MeSH terms
Adolescent; Adult; Aged; Child; Child, Preschool; Diabetic Ketoacidosis; Electrolytes; Female; Humans; Hypertonic Solutions; Hypotonic Solutions; Insulin; Isotonic Solutions; Male; Middle Aged; Osmolar Concentration; Plasma
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