The VkVI subgroup of rabbit light chains: complete amino acid sequence of a third variable region (K29-213).
Scand J Immunol, 1979;9(2):105-14.
PMID: 106464
Impact factor: 3.889
Abstract
The amino acid sequence of the variable region of a rabbit anti-streptococcal A-variant antibody light chain was determined. By using a combination of different cleavage methods, the sequence was established. Large peptides were sequenced in an extensively modified Beckman sequentor. Light chain K29-213 belongs to a rare subgroup (kVI). Several of these light chains of antibodies with different specificities have been totally or partially sequenced. Comparison of these light chains reveals at least four germ-line-encoded variants within this subgroup.
MeSH terms
Amino Acid Sequence; Animals; Antibodies, Bacterial; Antibody Specificity; Immunoglobulin Light Chains; Immunoglobulin kappa-Chains; Polysaccharides, Bacterial; Rabbits; Streptococcus pyogenes
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