Pneumococcal antigen in pneumonia. A post-mortem study with the histological and bacteriological findings.
Postgrad Med J, 1976/8;52(610):497-500.
El-Refaie M, Tait R, Dulake C, Dische FE
PMID: 10565
Impact factor: 4.973
Abstract
Pneumococcal capsular antigens can be detected in lung tissue by counter-current immunoelectrophoresis even when, following antibiotics, post-mortem bacterilogy suggests that Escherichia coli has replaced pneumococci. The results suggest that antipneumococcal therapy would benefit at least 55% of patients critically ill with lung infection and that the potentially toxic drugs directed at coliform bacteria may be unnecessary.
MeSH terms
Aged; Antigens, Bacterial; Counterimmunoelectrophoresis; Escherichia coli; Humans; Infant; Male; Middle Aged; Pneumonia; Streptococcus pneumoniae
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