Effects of intrafollicular administration of gonadotropins in two species of nonhuman primates using laparoscopy.
J Med Primatol, 1978;7(4):223-7.
PMID: 105138
Impact factor: 0.821
Abstract
Direct administration of 0.5 IU of human chorionic gonadotropin (HCG) into the matured ovarian follicles of adult female Saimiri sciureus resulted in ovulation in 45% of the animals treated. When purified ovine luteinizing hormone (LH) was administered, ovulation was observed in 55% of the animals while intrafollicular injection of saline had no effect. Similar injections of HCG into matured follicles of Macaca fascicularis would not cause ovulation but did result in a 55% increase in menstrual cycle length. These results indicate that the necessity of a primate source of LH for inducing ovulation may be due to an extrafollicular mechanism.
MeSH terms
Animals; Chorionic Gonadotropin; Female; Follicle Stimulating Hormone; Haplorhini; Injections; Laparotomy; Luteinizing Hormone; Macaca; Macaca fascicularis; Ovarian Follicle; Ovulation Induction; Saimiri
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