Genetic control of the immune response to the GAT terpolymer. I. Interstrain and interspecies cross-reactive idiotype.
Ann Immunol (Paris), 1978/7-1978/9;129 C(5):721-6.
PMID: 104654
Abstract
An antiidiotypic antiserum specific for the GAT antibodies of BALB/c mice has been obtained in rabbits. This serum recognizes the GAT idiotype of 13 inbred strains of mice as well as the GAT idiotype present in sera of guinea-pigs, rats and rabbits immunized with GAT. Such an antiidiotypic antiserum should serve as a good reagent to detect putative idiotypic determinants on GAT-specific suppressor factor.
MeSH terms
Animals; Antibody Specificity; Cross Reactions; Genes, MHC Class II; Guinea Pigs; Immune Sera; Immunoglobulin Idiotypes; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Peptides; Rabbits; Rats; Species Specificity
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