Heavy metal nephropathy of rodents.

Vet Pathol, 1978/8;15 Suppl 5:51-87.

Payne BJ, Saunders LZ

PMID: 104422

Impact factor: 3.157

Abstract
Heavy metal nephropathy is a pathologic entity of the renal tubular epithelium of rats, evoked by lead, gold, and other heavy metals. It is characterized acutely by coagulative necrosis, subacutely by cortical fibrosis, and chronically by cytomegaly and karyomegaly. Finally, adenomas develop, some of which become malignant.
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