Waldenström's macroglobulinaemia with Ig E M-component.
Scand J Haematol, 1978/10;21(4):292-8.
Shirakura T, Takekoshi K, Umi M, Kanazawa K, Okabe H, Inoue T, Imamura Y
PMID: 103186
Abstract
A case of Waldenström's macroglobulinaemia with Ig E M-component was presented. A 76-year-old Japanese woman had a history of the operation for mammary carcinoma. Although neither lymphadenopathy nor hepatosplenomegaly was present, the immunohaematological findings typical for Waldenström's macroglobulinaemia were observed in this patient. Coexistence of the Ig M and Ig E M-components was recognized in the patient's serum protein. Positive reaction for FITC-conjugated anti-epsilon or rhodamine-conjugated anti-mu was noted in proliferating lymphoplasmacytic cells of the patient's bone marrow, but these reactions were not simultaneously observed in a single cell. The finding suggests that two separate populations of M-component-producing cells were present.
MeSH terms
Aged; Bone Marrow; Breast Neoplasms; Chromatography, Gel; Female; Humans; Immunoelectrophoresis; Immunoglobulin E; Immunoglobulin M; Waldenstrom Macroglobulinemia
More resources
EndNote: Download