Turnover of rat liver malic enzyme during induction by protein deprivation.
Biochim Biophys Acta, 1978/9/27;520(2):452-9.
PMID: 101247
Abstract
The half-lives of hepatic malic enzyme and total liver soluble proteins were determined in protein-sufficient and protein-deficient rats after injection of tracer doses of radioactively labeled leucine. The results obtained in these experiments have demonstrated that the increased levels of malic enzyme obtained under conditions of severe protein restriction are due to elevated rates of synthesis of the enzyme protein, with no apparent change in the rate of its degradation.
MeSH terms
Animals; Enzyme Induction; Half-Life; Kinetics; Leucine; Liver; Malate Dehydrogenase; Male; Protein-Energy Malnutrition; Rats
More resources
EndNote: Download