Unusual evidence of myocardial involvement during a hypersensitivity reaction to oral penicillin.
Isr J Med Sci, 1978/8;14(8):848-51.
PMID: 100472
Abstract
A hypersensitivity reaction to orally administered phenoxymethyl penicillin is reported. The manifestations of the reaction included fever, arthralgia, urticaria and an irregular pulse. Serial ECG showed second-degree atrioventricular block with junctional escape beats, an atypical Wenckebach pattern and, finally, first-degree atrioventricular block with gradually decreasing PR intervals. A normal tracing was recorded on the sixth day despite the persistence of the rash and joint pains.
MeSH terms
Adult; Drug Hypersensitivity; Heart Block; Humans; Male; Penicillin V; Streptococcal Infections; Streptococcus pyogenes
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