[The effect of anesthetics on the basal secretion of immunoreactive growth hormone in rats].
C R Acad Hebd Seances Acad Sci D, 1978/6/12;286(23):1707-10.
PMID: 100239
Abstract
The authors investigated basal levels of plasma immunoreactive growth-hormone in the rat (R-GH) after administration of 3 different anesthetic drugs: urethan, chloral hydrate and gamma-hdroxy-butyrate (GHB). Lowest R-GH concentrations (5 +/- 3 ng/ml) are observed after urethan; they are significantly higher (15 +/- 4 ng/ml) after chloral hydrate but this anesthetic also causes hyperglycemia (210 +/- 30 mg/100 ml). Normal blood glucose levels are observed under GHB narco-analgesia which elicits a clear-cut R-GH secretory episode (70 +/- 5 ng/ml); basal values (12 +/- 3 ng/ml) are maintained for several hours thereafter.
MeSH terms
Anesthetics; Animals; Blood Glucose; Chloral Hydrate; Growth Hormone; Hydroxybutyrates; Male; Pituitary Gland; Rats; Time Factors; Urethane
More resources
EndNote: Download